Pain Relievers: Over-the-counter pain relievers like ibuprofen (Advil) or acetaminophen (Tylenol) can help reduce pain and inflammation. Follow the instructions on the label and consult a healthcare professional if you have any health conditions or are taking other medications. Saltwater Rinse: Dissolve half a teaspoon of salt in 8 ounces of warm water and use it as a mouthwash. This can help reduce inflammation and provide temporary relief.